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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
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- Product number
- ABIN616771 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD46 Molecule, Complement Regulatory Protein (CD46) antibody (Biotin)
- Antibody type
- Monoclonal
- Reactivity
- Human, Bovine
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- MEM-258
- Vial size
- 0.1 mg
- Storage
- Store the antibody prior to reconstitution at -20°C. Following reconstitution the antibody can be stored at 2-8°C for one month or at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35.
Receptor usage of a newly emergent adenovirus type 14.
Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes adenovirus host co-existence.
Evaluation of twenty-one human adenovirus types and one infectivity-enhanced adenovirus for the treatment of malignant melanoma.
Species B adenovirus serotypes 3, 7, 11 and 35 share similar binding sites on the membrane cofactor protein CD46 receptor.
Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses.
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.
Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation.
Monoclonal antibody detection of CD46 clustering beneath Neisseria gonorrhoeae microcolonies.
Emerging roles and new functions of CD46.
The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35.
CD46 is a cellular receptor for group B adenoviruses.
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation.
Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.
Kälin S, Amstutz B, Gastaldelli M, Wolfrum N, Boucke K, Havenga M, DiGennaro F, Liska N, Hemmi S, Greber UF
Journal of virology 2010 May;84(10):5336-50
Journal of virology 2010 May;84(10):5336-50
Receptor usage of a newly emergent adenovirus type 14.
Wang H, Tuve S, Erdman DD, Lieber A
Virology 2009 May 10;387(2):436-41
Virology 2009 May 10;387(2):436-41
Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes adenovirus host co-existence.
Rebetz J, Na M, Su C, Holmqvist B, Edqvist A, Nyberg C, Widegren B, Salford LG, Sjögren HO, Arnberg N, Qian Q, Fan X
PloS one 2009 Dec 29;4(12):e8484
PloS one 2009 Dec 29;4(12):e8484
Evaluation of twenty-one human adenovirus types and one infectivity-enhanced adenovirus for the treatment of malignant melanoma.
Hoffmann D, Bayer W, Heim A, Potthoff A, Nettelbeck DM, Wildner O
The Journal of investigative dermatology 2008 Apr;128(4):988-98
The Journal of investigative dermatology 2008 Apr;128(4):988-98
Species B adenovirus serotypes 3, 7, 11 and 35 share similar binding sites on the membrane cofactor protein CD46 receptor.
Fleischli C, Sirena D, Lesage G, Havenga MJ, Cattaneo R, Greber UF, Hemmi S
The Journal of general virology 2007 Nov;88(Pt 11):2925-34
The Journal of general virology 2007 Nov;88(Pt 11):2925-34
Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses.
Loré K, Adams WC, Havenga MJ, Precopio ML, Holterman L, Goudsmit J, Koup RA
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1721-9
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 1;179(3):1721-9
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.
Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, Arzouk N, Cleper R, Francois M, Guest G, Pourrat J, Seligman R, Fridman WH, Loirat C, Atkinson JP
Journal of the American Society of Nephrology : JASN 2006 Jul;17(7):2017-25
Journal of the American Society of Nephrology : JASN 2006 Jul;17(7):2017-25
Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation.
Oliaro J, Pasam A, Waterhouse NJ, Browne KA, Ludford-Menting MJ, Trapani JA, Russell SM
Proceedings of the National Academy of Sciences of the United States of America 2006 Dec 5;103(49):18685-90
Proceedings of the National Academy of Sciences of the United States of America 2006 Dec 5;103(49):18685-90
Monoclonal antibody detection of CD46 clustering beneath Neisseria gonorrhoeae microcolonies.
Weyand NJ, Lee SW, Higashi DL, Cawley D, Yoshihara P, So M
Infection and immunity 2006 Apr;74(4):2428-35
Infection and immunity 2006 Apr;74(4):2428-35
Emerging roles and new functions of CD46.
Liszewski MK, Kemper C, Price JD, Atkinson JP
Springer seminars in immunopathology 2005 Nov;27(3):345-58
Springer seminars in immunopathology 2005 Nov;27(3):345-58
The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35.
Fleischli C, Verhaagh S, Havenga M, Sirena D, Schaffner W, Cattaneo R, Greber UF, Hemmi S
Journal of virology 2005 Aug;79(15):10013-22
Journal of virology 2005 Aug;79(15):10013-22
CD46 is a cellular receptor for group B adenoviruses.
Gaggar A, Shayakhmetov DM, Lieber A
Nature medicine 2003 Nov;9(11):1408-12
Nature medicine 2003 Nov;9(11):1408-12
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation.
Marie JC, Astier AL, Rivailler P, Rabourdin-Combe C, Wild TF, Horvat B
Nature immunology 2002 Jul;3(7):659-66
Nature immunology 2002 Jul;3(7):659-66
Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.
Okada N, Liszewski MK, Atkinson JP, Caparon M
Proceedings of the National Academy of Sciences of the United States of America 1995 Mar 28;92(7):2489-93
Proceedings of the National Academy of Sciences of the United States of America 1995 Mar 28;92(7):2489-93
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