Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- BAF2255 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal LDLR Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse LDL R in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human LDL R is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.
Seidah NG, Poirier S, Denis M, Parker R, Miao B, Mapelli C, Prat A, Wassef H, Davignon J, Hajjar KA, Mayer G
PloS one 2012;7(7):e41865
PloS one 2012;7(7):e41865
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of LDL R in RAW 264.7 Mouse Cell Line by Flow Cytometry. Serum-deprived RAW 264.7 mouse monocyte/macrophage cell line was stained with Goat Anti-Mouse LDL R Biotinylated Antigen Affinity-purified Polyclonal Antibody (Catalog # BAF2255, filled histogram) or isotype control antibody (Catalog # BAF108, open histogram), followed by Streptavidin-PE (Catalog # F0040).