FAB4681A-100

antibody from R&D Systems

Targeting: IL6ST CD130, GP130, sGP130

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

FAB4681A-100

Provider

R&D Systems

Product name

Mouse gp130 APC-conjugated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse gp130 in direct ELISAs and Western blots

Reactivity

Mouse

Host

Rat

Conjugate

Red dye

Antigen sequence

Q6PDI9


Isotype

IgG

Antibody clone number

125623

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

References

Submitted references

TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development.

Nagashima H, Okuyama Y, Hayashi T, Ishii N, So T
Journal of immunology (Baltimore, Md. : 1950) 2016 May 15;196(10):4082-9

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MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.

Pratama A, Srivastava M, Williams NJ, Papa I, Lee SK, Dinh XT, Hutloff A, Jordan MA, Zhao JL, Casellas R, Athanasopoulos V, Vinuesa CG
Nature communications 2015 Mar 6;6:6436

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The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.

Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, Croft M, Ishii N, So T
Nature immunology 2014 May;15(5):449-56

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Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages.

Liao W, Lin JX, Wang L, Li P, Leonard WJ
Nature immunology 2011 Jun;12(6):551-9

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IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.

Silver JS, Stumhofer JS, Passos S, Ernst M, Hunter CA
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 1;187(1):350-60