ABIN1383678

antibody from antibodies-online

Targeting: IL6ST CD130, GP130, sGP130

No application information provided.

Antibody Data

Product number

ABIN1383678

Provider

antibodies-online

Product name

anti-Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) antibody

Antibody type

Monoclonal

Antigen

Other

Reactivity

Human

Isotype

IgG

Antibody clone number

B-R3

Vial size

200 µl

Concentration

200µg/200µl

Storage

2-8°C

References

Submitted references

Akt signaling pathway: a target for radiosensitizing human malignant glioma.

Chautard E, Loubeau G, Tchirkov A, Chassagne J, Vermot-Desroches C, Morel L, Verrelle P
Neuro-oncology 2010 May;12(5):434-43

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N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.

Waetzig GH, Chalaris A, Rosenstiel P, Suthaus J, Holland C, Karl N, Vallés Uriarte L, Till A, Scheller J, Grötzinger J, Schreiber S, Rose-John S, Seegert D
The Journal of biological chemistry 2010 Jan 15;285(3):1781-9

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In vivo modulation of soluble "antagonistic" IL-6 receptor synthesis and release in ESRD.

Memoli B, Grandaliano G, Soccio M, Postiglione L, Guida B, Bisesti V, Esposito P, Procino A, Marrone D, Michael A, Andreucci M, Schena FP, Pertosa G
Journal of the American Society of Nephrology : JASN 2005 Apr;16(4):1099-107

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Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.

Duplomb L, Chaigne-Delalande B, Vusio P, Raher S, Jacques Y, Godard A, Blanchard F
Endocrinology 2003 Dec;144(12):5381-9

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Down-regulation of human CYP3A4 by the inflammatory signal interleukin-6: molecular mechanism and transcription factors involved.

Jover R, Bort R, Gómez-Lechón MJ, Castell JV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Nov;16(13):1799-801

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Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma.

Burger R, Guenther A, Bakker F, Schmalzing M, Bernand S, Baum W, Duerr B, Hocke GM, Steininger H, Gebhart E, Gramatzki M
The hematology journal : the official journal of the European Haematology Association / EHA 2001;2(1):42-53

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Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.

Aoki Y, Narazaki M, Kishimoto T, Tosato G
Blood 2001 Nov 15;98(10):3042-9

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Identification of agonistic and antagonistic antibodies against gp190, the leukemia inhibitory factor receptor, reveals distinct roles for its two cytokine-binding domains.

Taupin JL, Legembre P, Bitard J, Daburon S, Pitard V, Blanchard F, Duplomb L, Godard A, Jacques Y, Moreau JF
The Journal of biological chemistry 2001 Dec 21;276(51):47975-81

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STAT3 is constitutively activated in Hodgkin cell lines.

Kube D, Holtick U, Vockerodt M, Ahmadi T, Haier B, Behrmann I, Heinrich PC, Diehl V, Tesch H
Blood 2001 Aug 1;98(3):762-70

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Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors.

Gu ZJ, De Vos J, Rebouissou C, Jourdan M, Zhang XG, Rossi JF, Wijdenes J, Klein B
Leukemia 2000 Jan;14(1):188-97

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Identification of a gp130 cytokine receptor critical site involved in oncostatin M response.

Olivier C, Auguste P, Chabbert M, Lelièvre E, Chevalier S, Gascan H
The Journal of biological chemistry 2000 Feb 25;275(8):5648-56

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Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies.

Müller-Newen G, Küster A, Wijdenes J, Schaper F, Heinrich PC
The Journal of biological chemistry 2000 Feb 18;275(7):4579-86

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Mannose 6-Phosphate/Insulin-like growth factor II receptor mediates internalization and degradation of leukemia inhibitory factor but not signal transduction.

Blanchard F, Duplomb L, Raher S, Vusio P, Hoflack B, Jacques Y, Godard A
The Journal of biological chemistry 1999 Aug 27;274(35):24685-93

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Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway.

Thiel S, Behrmann I, Dittrich E, Muys L, Tavernier J, Wijdenes J, Heinrich PC, Graeve L
The Biochemical journal 1998 Feb 15;330 ( Pt 1):47-54

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Signaling of type II oncostatin M receptor.

Auguste P, Guillet C, Fourcin M, Olivier C, Veziers J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1997 Jun 20;272(25):15760-4

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Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties.

Lebeau B, Montero Julian FA, Wijdenes J, Müller-Newen G, Dahmen H, Chérel M, Heinrich PC, Brailly H, Hallet MM, Godard A, Minvielle S, Jacques Y
FEBS letters 1997 Apr 28;407(2):141-7

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Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop.

Gu ZJ, Costes V, Lu ZY, Zhang XG, Pitard V, Moreau JF, Bataille R, Wijdenes J, Rossi JF, Klein B
Blood 1996 Nov 15;88(10):3972-86

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Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M.

Gu ZJ, Wijdenes J, Zhang XG, Hallet MM, Clement C, Klein B
Journal of immunological methods 1996 Mar 28;190(1):21-7

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Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein.

Chevalier S, Fourcin M, Robledo O, Wijdenes J, Pouplard-Barthelaix A, Gascan H
The Journal of biological chemistry 1996 Jun 21;271(25):14764-72