DPABH-27278

antibody from Creative Diagnostics

Targeting: RBFOX1 A2BP1, FOX-1, HRNBP1

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-27278

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-27278, RRID:AB_2507837

Product name

Rabbit Anti-Human RBFOX1 Polyclonal Antibody

Antibody type

Polyclonal

Description

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.