Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- orb42303 - Provider product page
- Provider
- Biorbyt
- Product name
- Anti-CNTN1 antibody
- Antibody type
- Monoclonal
- Description
- Mouse Monoclonal to CNTN1. Human contactin-1 (CNTN1) is a member of the contactin subfamily belonging to the immunoglobulin superfamily. CNTN1 is a glycosylphosphatidylinositol-anchored neuronal membrane protein and is expressed in numerous neuronal tissues and cell lines. As a cell adhesion molecule, CNTN1 plays a key role in the formation of axon connections in the developing nervous system. It has been demonstrated that CNTN1 contributes to signal pathways via its association with Contactin-associated protein, receptor protein tyrosine phosphatase beta and NOTCH1, and is involved in paranodal axo-glial junction formation and oligodendrocytes generation. Furthermore, studies have indicated that CNTN1 functions prominently in the invasion and metastasis of lung adenocarcinoma cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 200 μg, 100 μg, 50 μg
- Storage
- This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of 293 cell line lysate using CNTN1 antibody; The detection limit for CNTN1 is approximately 8ng /lane under non-reducing conditions.
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of 293 cell line lysate using CNTN1 antibody; The detection limit for CNTN1 is approximately 8ng /lane under reducing conditions.