Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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Validation data
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- Product number
- orb137133 - Provider product page
- Provider
- Biorbyt
- Product name
- ADAM 17 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal to ADAM 17. This gene encodes a disintegrin and metalloprotease (ADAM) domain 17, which is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. This gene contains 19 exons and alternative splicing generates 2 transcripts.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20 μl, 50 μl, 100 μl
- Concentration
- 1 mg/ml
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Supportive validation
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- Biorbyt (provider)
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- Experimental details
- Western blot analysis of HT1080 whole cell lysate using ADAM 17 antibody