DPABH-25755

antibody from Creative Diagnostics

Targeting: WNT4 WNT-4

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-25755

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-25755, RRID:AB_2518919

Product name

Rabbit Anti-Human WNT4 Polyclonal Antibody

Antibody type

Polyclonal

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.