orb152740

antibody from Biorbyt
Targeting: SCNN1B ENaCbeta
Provider product page for orb152740
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
orb152740 - Provider product page
Provider
Biorbyt
Product name
ENaC Beta antibody (Streptavidin)
Antibody type
Polyclonal
Description
Rabbit polyclonal to ENaC Beta (Streptavidin). The Epithelial Sodium Channel (ENaC) is a membrane ion channel permeable to Na+ ions. It is located in the apical plasma membrane of epithelia in the kidneys, lung, colon, and other tissues where it plays a role in trans epithelial Na+-ion transport. Specifically Na+ transport via ENaC occurs across many epithelial surfaces, and plays a key role in regulating salt and water absorption. ENaCs are composed of three structurally related subunits that form a tetrameric channel, alpha, beta , and gamma. The expression of its alpha and beta subunits is enhanced as keratinocytes differentiate. The beta and gamma-ENaC subunits are essential for edema fluid to exert its maximal effect on net fluid absorption by distal lung epithelia(5). And it has been concluded that the subunits are differentially expressed in the retina of mice with ocular hypertension, therefore the up-regulation of alpha-ENaC proteins could serve as a protection mechanism against elevated intraocular pressure..
Reactivity
Human, Mouse, Rat
Host
Rabbit
Vial size
100 μg
Concentration
1 mg/ml
Storage
Store at 2-8°C and -20°C for one year. (Shipped on ice packs)
SCNN1B protein structure - orb152740 shown in red.