NBP2-75781

antibody from Novus Biologicals
Targeting: GP2 ZAP75
Provider product page for NBP2-75781

Antibody data

Product number
NBP2-75781 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal GP2 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
100 ug
Concentration
0.2 mg/ml
Storage
Store at 4C.
GP2 protein structure - NBP2-75781 shown in red.