orb137931

antibody from Biorbyt

Targeting: LAT LAT1

Western blot

Immunocytochemistry

Antibody data

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Validation data

Product number: orb137931 - Provider product page
Provider: Biorbyt
Product name: LAT antibody
Antibody type: Polyclonal
Description: Rabbit polyclonal to LAT. Linker for activation of T cells, also known as LAT, is a protein which in humans is encoded by the LAT gene. This gene is mapped to 16p11.2. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 μg
Storage: Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.

LAT protein structure - orb137931 shown in red.