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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA5-37773 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Phospho-PERK (Thr982) Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- A suggested positive control for IHC is human prostate carcinoma.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- -20°C
Submitted references Endoplasmic Reticulum Stress Is Involved in Glucocorticoid-Induced Apoptosis in PC12 Cells.
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.
Yi S, Shi W, Zuo M, Wang S, Ma R, Bi H, Cong B, Li Y
Analytical cellular pathology (Amsterdam) 2021;2021:5565671
Analytical cellular pathology (Amsterdam) 2021;2021:5565671
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.
Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB
Nature communications 2017 Oct 20;8(1):1079
Nature communications 2017 Oct 20;8(1):1079
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Phospho-PERK (Thr982) in paraffin-embedded Human prostate carcinoma tissue using Phospho-PERK (Thr982) Polyclonal Antibody (Product # PA5-37773) (left) or the same antibody preincubated with blocking peptide (right).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 4 (a, b) Representative images showing p-PERK and p-IRE1 immunofluorescence in PC12 cells. (c, d) The average IOD of p-PERK and p-IRE1 per cell. Bars = 25 mu m (magnification: x800). The data are shown as the mean +- SEM, ** P < 0.01 compared with the control group; # P < 0.01, ## P < 0.01 compared with the DEX group. PERK: PKR-like endoplasmic reticulum kinase; IRE1: inositol requirement 1; DEX: dexamethasone; 4-PBA: 4-phenylbutyric acid.
