Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- AF4320 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal LAMP-1/CD107a Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse LAMP1/CD107a Lumenal Domain in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human LAMP1 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.
Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.
Zhang J, Johnson JL, He J, Napolitano G, Ramadass M, Rocca C, Kiosses WB, Bucci C, Xin Q, Gavathiotis E, Cuervo AM, Cherqui S, Catz SD
The Journal of biological chemistry 2017 Jun 23;292(25):10328-10346
The Journal of biological chemistry 2017 Jun 23;292(25):10328-10346
Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.
Koike M, Shibata M, Sunabori T, Yamaguchi J, Sakimura K, Komatsu M, Tanaka K, Uchiyama Y
The American journal of pathology 2017 Jul;187(7):1586-1600
The American journal of pathology 2017 Jul;187(7):1586-1600
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Mouse LAMP-1/CD107a by Western Blot. Detection of Mouse LAMP-1/CD107a by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of LAMP-1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. Detection of LAMP-1 in RAW 264.7 Mouse Cell Line by Flow Cytometry.