Antibody data

Product number
328618
Provider
BioLegend
Proper citation
BioLegend Cat#328618, RRID:AB_11147955
Product name
PE/Cy7 anti-human CD107a (LAMP-1)
Provider product page
BioLegend - 328618
Antibody type
Monoclonal
Antigen
Human adult adherent peripheral blood cells
Description
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane gly­coprotein. The mature CD107a is heavily glycosylated from a 40 kD core protein. It is expressed by activated platelets, acti­vated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. This molecule is located on the luminal side of lysosomes and has been suggested to play a role in the protection of lysosomes membrane from lysosomal hydrolases. Upon activation, CD107a is transferred to the cell membrane surface. It plays a role in cell adhesion and regula­tion of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Infrared dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -