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LearnNB100-65332IR
antibody from Novus Biologicals
Targeting: PDCD1LG2
B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2
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- Antibody Data
- Antigen structure
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- Product number
- NB100-65332IR - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal PD-L2/B7-DC/PDCD1LG2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Near infrared dye
- Isotype
- IgG
- Vial size
- 0.125 ml
- Storage
- Store at 4C in the dark.
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