329605

antibody from BioLegend
Targeting: PDCD1LG2 B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2
Provider product page for 329605

Antibody data

Product number
329605 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#329605, RRID:AB_1089021
Product name
PE anti-human CD273 (B7-DC, PD-L2)
Antibody type
Monoclonal
Antigen
Human PD-L2 cDNA
Description
CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
PDCD1LG2 protein structure - 329605 shown in red.