354004

antibody from BioLegend
Targeting: TIMD4 TIM4
Provider product page for 354004

Antibody data

Product number
354004 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#354004, RRID:AB_11124105
Product name
PE anti-human Tim-4
Antibody type
Monoclonal
Antigen
Human TIM-4- IgV Fc, fusion protein
Description
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th-1 and Th-2) cell-mediated immunity. Tim-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of Tim-1. This binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and is connected to TIM-1-triggered Th2 responsiveness.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
TIMD4 protein structure - 354004 shown in red.