Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [8]
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- Product number
- NBP1-85710 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-85710, RRID:AB_11017021
- Product name
- Rabbit Polyclonal Desmocollin-2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Desmocollin-2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations.
Gehmlich K, Syrris P, Peskett E, Evans A, Ehler E, Asimaki A, Anastasakis A, Tsatsopoulou A, Vouliotis AI, Stefanadis C, Saffitz JE, Protonotarios N, McKenna WJ
Cardiovascular research 2011 Apr 1;90(1):77-87
Cardiovascular research 2011 Apr 1;90(1):77-87
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human kidney shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human liver shows weak membranous positivity in hepatocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human esophagus shows strong membranous positivity in squamous epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining in human esophagus and cerebral cortex tissues.. Corresponding DSC2 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human tonsil shows strong membranous positivity in squamous epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human cerebral cortex shows no positivity in neurons as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human colon, esophagus, liver and tonsil using Anti-DSC2 antibody NBP1-85710 (A) shows similar protein distribution across tissues to independent antibody NBP1-85711 (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Desmocollin-2 Antibody [NBP1-85710] - Staining of human colon shows moderate membranous positivity in glandular cells.