ABIN968064

antibody from antibodies-online

Targeting: IQGAP1 HUMORFA01, KIAA0051, p195, SAR1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN968064

Provider

antibodies-online

Product name

anti-IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) (AA 1348-1490) antibody

Antibody type

Monoclonal

Antigen

Human IQGAP1

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

24

Vial size

150 µg

Concentration

250 µg/ml

Storage

Store undiluted at -20° C.

References

Submitted references

The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin.

Ruiz-Velasco R, Lanning CC, Williams CL
The Journal of biological chemistry 2002 Sep 6;277(36):33081-91

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The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes.

Mbele GO, Deloulme JC, Gentil BJ, Delphin C, Ferro M, Garin J, Takahashi M, Baudier J
The Journal of biological chemistry 2002 Dec 20;277(51):49998-50007

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Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1.

Li S, Wang Q, Chakladar A, Bronson RT, Bernards A
Molecular and cellular biology 2000 Jan;20(2):697-701

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Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1.

Kuroda S, Fukata M, Kobayashi K, Nakafuku M, Nomura N, Iwamatsu A, Kaibuchi K
The Journal of biological chemistry 1996 Sep 20;271(38):23363-7

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IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs.

Hart MJ, Callow MG, Souza B, Polakis P
The EMBO journal 1996 Jun 17;15(12):2997-3005