PFBL-457

antibody from Creative Biolabs

Targeting: ECD GCR2, hSGT1

No application information provided.

Antibody Data

Product number

PFBL-457

Provider

Creative Biolabs

Product name

Human Anti-ECD Recombinant Antibody (clone mAb23); Fab Fragment

Antibody type

Monoclonal

Description

Recombinant Human Antibody (mAb23) Fab Fragment is specific to ECD, expressed in Chinese Hamster Ovary cells (CHO). This Fab fragment blocks glucagon binding and inhibits basal receptor activity, indicating that it is an inverse agonist and that the ECD can negatively regulate receptor activity independent of ligand binding.

Reactivity

Human

Host

Human

Storage

Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.