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- Antigen structure
- References [6]
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- Product number
- ABIN264843 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) antibody
- Antibody type
- Polyclonal
- Description
- Affinity Chromatography on Protein G
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 0.1 mg
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function.
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
GABAB-receptor splice variants GB1a and GB1b in rat brain: developmental regulation, cellular distribution and extrasynaptic localization.
Kniazeff J, Galvez T, Labesse G, Pin JP
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Sep 1;22(17):7352-61
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002 Sep 1;22(17):7352-61
Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function.
Galvez T, Duthey B, Kniazeff J, Blahos J, Rovelli G, Bettler B, Prézeau L, Pin JP
The EMBO journal 2001 May 1;20(9):2152-9
The EMBO journal 2001 May 1;20(9):2152-9
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Ng GY, Bertrand S, Sullivan R, Ethier N, Wang J, Yergey J, Belley M, Trimble L, Bateman K, Alder L, Smith A, McKernan R, Metters K, O'Neill GP, Lacaille JC, Hébert TE
Molecular pharmacology 2001 Jan;59(1):144-52
Molecular pharmacology 2001 Jan;59(1):144-52
Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
Margeta-Mitrovic M, Jan YN, Jan LY
Proceedings of the National Academy of Sciences of the United States of America 2001 Dec 4;98(25):14649-54
Proceedings of the National Academy of Sciences of the United States of America 2001 Dec 4;98(25):14649-54
Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
Margeta-Mitrovic M, Jan YN, Jan LY
Proceedings of the National Academy of Sciences of the United States of America 2001 Dec 4;98(25):14643-8
Proceedings of the National Academy of Sciences of the United States of America 2001 Dec 4;98(25):14643-8
GABAB-receptor splice variants GB1a and GB1b in rat brain: developmental regulation, cellular distribution and extrasynaptic localization.
Fritschy JM, Meskenaite V, Weinmann O, Honer M, Benke D, Mohler H
The European journal of neuroscience 1999 Mar;11(3):761-8
The European journal of neuroscience 1999 Mar;11(3):761-8
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