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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations [0]
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- Product number
- ABIN117957 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 94-108), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Delipidation and defibrination.
- Reactivity
- Human, Mouse, Zebrafish
- Host
- Rabbit
- Antigen sequence
Human ROC1 (108 aa 12.2 kDa) : 1 ma
aamdvdtp sgtnsgagkk rfevkkwnav a
lwawdivvd ncaicrnhim dlciecqanq
61 asatseectv awgvcnhafh fhcisrwl
kt rqvcpldnre wefqkygh- Epitope
- C-Term, AA 94-108
- Vial size
- 0.1 mL
- Storage
- Store undiluted at 2-8°C.
Submitted references Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Ubiquitin and its kin: how close are the family ties?
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
Genomic organization and expression of the ubiquitin-proteasome complex-associated protein Rbx1/ROC1/Hrt1.
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Wertz IE, O'Rourke KM, Zhang Z, Dornan D, Arnott D, Deshaies RJ, Dixit VM
Science (New York, N.Y.) 2004 Feb 27;303(5662):1371-4
Science (New York, N.Y.) 2004 Feb 27;303(5662):1371-4
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.
Yu X, Yu Y, Liu B, Luo K, Kong W, Mao P, Yu XF
Science (New York, N.Y.) 2003 Nov 7;302(5647):1056-60
Science (New York, N.Y.) 2003 Nov 7;302(5647):1056-60
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP
Nature 2002 Apr 18;416(6882):703-9
Nature 2002 Apr 18;416(6882):703-9
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
Furukawa M, Zhang Y, McCarville J, Ohta T, Xiong Y
Molecular and cellular biology 2000 Nov;20(21):8185-97
Molecular and cellular biology 2000 Nov;20(21):8185-97
Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G
Trends in cell biology 2000 Aug;10(8):335-42
Trends in cell biology 2000 Aug;10(8):335-42
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ
Genes & development 1999 Jun 15;13(12):1614-26
Genes & development 1999 Jun 15;13(12):1614-26
Genomic organization and expression of the ubiquitin-proteasome complex-associated protein Rbx1/ROC1/Hrt1.
Périn J-P, Seddiqi N, Charbonnier F, Goudou D, Belkadi L, Rieger F, Alliel PM
Cellular and molecular biology (Noisy-le-Grand, France) 1999 Dec;45(8):1131-7
Cellular and molecular biology (Noisy-le-Grand, France) 1999 Dec;45(8):1131-7
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ
Molecular cell 1999 Apr;3(4):527-33
Molecular cell 1999 Apr;3(4):527-33
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW
Science (New York, N.Y.) 1999 Apr 23;284(5414):662-5
Science (New York, N.Y.) 1999 Apr 23;284(5414):662-5
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG Jr, Elledge SJ, Conaway RC, Harper JW, Conaway JW
Science (New York, N.Y.) 1999 Apr 23;284(5414):657-61
Science (New York, N.Y.) 1999 Apr 23;284(5414):657-61
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