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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 350119 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#350119, RRID:AB_2566445
- Product name
- Brilliant Violet 510™ anti-human CD294 (CRTH2)
- Antibody type
- Monoclonal
- Antigen
- Rat cell line TART/B19-12.10 transfected with human CRTH2
- Description
- CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Green dye
- Antibody clone number
- BM16
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD4 APC, CCR4 PerCp/Cy5.5, and CD294 (clone BM16) Brilliant Violet 510™ (top) or rat IgG2a, κ Brilliant Violet 510™ isotype control (bottom). Data shown was gated on the CD4+ population.
- Conjugate
- Green dye
