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Correa RJ, Valdes YR, Peart TM, Fazio EN, Bertrand M, McGee J, Préfontaine M, Sugimoto A, DiMattia GE, Shepherd TG
Carcinogenesis 2014 Sep;35(9):1951-61

SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth.

Ma L, Maruwge W, Strambi A, D'Arcy P, Pellegrini P, Kis L, de Milito A, Lain S, Brodin B
Cell death & disease 2014 Oct 23;5:e1483

Increased expression of p62/SQSTM1 in prion diseases and its association with pathogenic prion protein.

Homma T, Ishibashi D, Nakagaki T, Satoh K, Sano K, Atarashi R, Nishida N
Scientific reports 2014 Mar 28;4:4504

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression.

Gómez-Sánchez R, Gegg ME, Bravo-San Pedro JM, Niso-Santano M, Alvarez-Erviti L, Pizarro-Estrella E, Gutiérrez-Martín Y, Alvarez-Barrientos A, Fuentes JM, González-Polo RA, Schapira AH
Neurobiology of disease 2014 Feb;62:426-40

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway.

Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV, Shen J
Molecular neurodegeneration 2012 Jan 9;7:2

Keap1 degradation by autophagy for the maintenance of redox homeostasis.

Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, Yamamoto M
Proceedings of the National Academy of Sciences of the United States of America 2012 Aug 21;109(34):13561-6

EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells.

Han W, Pan H, Chen Y, Sun J, Wang Y, Li J, Ge W, Feng L, Lin X, Wang X, Wang X, Jin H
PloS one 2011;6(6):e18691

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.

Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP
Nature immunology 2011 May;12(5):408-15

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL
Nature cell biology 2011 Feb;13(2):132-41

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.

Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL
Proceedings of the National Academy of Sciences of the United States of America 2010 Mar 2;107(9):4153-8

mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary.

Mabuchi S, Kawase C, Altomare DA, Morishige K, Sawada K, Hayashi M, Tsujimoto M, Yamoto M, Klein-Szanto AJ, Schilder RJ, Ohmichi M, Testa JR, Kimura T
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Sep 1;15(17):5404-13

PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway.

Li C, Liu H, Sun Y, Wang H, Guo F, Rao S, Deng J, Zhang Y, Miao Y, Guo C, Meng J, Chen X, Li L, Li D, Xu H, Wang H, Li B, Jiang C
Journal of molecular cell biology 2009 Oct;1(1):37-45

MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy.

Balakumaran BS, Porrello A, Hsu DS, Glover W, Foye A, Leung JY, Sullivan BA, Hahn WC, Loda M, Febbo PG
Cancer research 2009 Oct 1;69(19):7803-10

Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion.

Deuretzbacher A, Czymmeck N, Reimer R, Trülzsch K, Gaus K, Hohenberg H, Heesemann J, Aepfelbacher M, Ruckdeschel K
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5847-60

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice.

Chen YF, Kao CH, Chen YT, Wang CH, Wu CY, Tsai CY, Liu FC, Yang CW, Wei YH, Hsu MT, Tsai SF, Tsai TF
Genes & development 2009 May 15;23(10):1183-94

CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization.

Roca H, Varsos ZS, Sud S, Craig MJ, Ying C, Pienta KJ
The Journal of biological chemistry 2009 Dec 4;284(49):34342-54

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