ABIN196801

antibody from antibodies-online

Targeting: MAPT DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN196801

Provider

antibodies-online

Product name

anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of threonine 181 (P-K-Tp-P-P).

Description

Affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pThr181

Vial size

50 μL

Concentration

1.0 mg/mL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation.

Pérez M, Ribe E, Rubio A, Lim F, Morán MA, Ramos PG, Ferrer I, Isla MT, Avila J
Neuroscience 2005;130(2):339-47

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Individual and regional variations of phospho-tau species in progressive supranuclear palsy.

Puig B, Rey MJ, Ferrer I
Acta neuropathologica 2005 Sep;110(3):261-8

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Association of elevated phospho-tau levels with Alzheimer-typical 18F-fluoro-2-deoxy-D-glucose positron emission tomography findings in patients with mild cognitive impairment.

Fellgiebel A, Siessmeier T, Scheurich A, Winterer G, Bartenstein P, Schmidt LG, Müller MJ
Biological psychiatry 2004 Aug 15;56(4):279-83

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Promotion of hyperphosphorylation by frontotemporal dementia tau mutations.

Alonso Adel C, Mederlyova A, Novak M, Grundke-Iqbal I, Iqbal K
The Journal of biological chemistry 2004 Aug 13;279(33):34873-81