DPABH-23593

antibody from Creative Diagnostics

Targeting: EIF3I eIF3-beta, eIF3-p36, EIF3S2, TRIP-1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DPABH-23593

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-23593, RRID:AB_2505574

Product name

Rabbit Anti-Human EIF3I Polyclonal antibody

Antibody type

Polyclonal

Description

Eukaryotic initiation factor (EIF3) complex is the largest of the eIFs and consists of more than 10 nonidentical subunit, and is required for several steps in the initiation of protein synthesis. It associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). Also it can stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3I is one subunit of EIF3 complex.

Reactivity

Human, Mouse, Rat, Hamster

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL