Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN195469 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tuberous Sclerosis 1 (TSC1) antibody
- Antibody type
- Polyclonal
- Antigen
- The synthetic peptide of a part of Human TSC1/Hamartin (GQLHIMDYNETHHEHS)
- Description
- Purified with antigen peptide
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
Submitted references TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth.
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.
Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles.
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.
Identification and characterization of the tuberous sclerosis gene on chromosome 16.
Gao X, Pan D
Genes & development 2001 Jun 1;15(11):1383-92
Genes & development 2001 Jun 1;15(11):1383-92
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.
Kobayashi T, Minowa O, Sugitani Y, Takai S, Mitani H, Kobayashi E, Noda T, Hino O
Proceedings of the National Academy of Sciences of the United States of America 2001 Jul 17;98(15):8762-7
Proceedings of the National Academy of Sciences of the United States of America 2001 Jul 17;98(15):8762-7
Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles.
Plank TL, Yeung RS, Henske EP
Cancer research 1998 Nov 1;58(21):4766-70
Cancer research 1998 Nov 1;58(21):4766-70
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.
van Slegtenhorst M, de Hoogt R, Hermans C, Nellist M, Janssen B, Verhoef S, Lindhout D, van den Ouweland A, Halley D, Young J, Burley M, Jeremiah S, Woodward K, Nahmias J, Fox M, Ekong R, Osborne J, Wolfe J, Povey S, Snell RG, Cheadle JP, Jones AC, Tachataki M, Ravine D, Sampson JR, Reeve MP, Richardson P, Wilmer F, Munro C, Hawkins TL, Sepp T, Ali JB, Ward S, Green AJ, Yates JR, Kwiatkowska J, Henske EP, Short MP, Haines JH, Jozwiak S, Kwiatkowski DJ
Science (New York, N.Y.) 1997 Aug 8;277(5327):805-8
Science (New York, N.Y.) 1997 Aug 8;277(5327):805-8
Identification and characterization of the tuberous sclerosis gene on chromosome 16.
European Chromosome 16 Tuberous Sclerosis Consortium
Cell 1993 Dec 31;75(7):1305-15
Cell 1993 Dec 31;75(7):1305-15
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