ABIN362355

antibody from antibodies-online

Targeting: EIF2S1 EIF-2alpha, EIF2, EIF2A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362355

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 2A (EIF2A) (pSer51) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer51 (E-L-S (p) -R-R) derived from Human eIF2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer51

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2.

Kubota H, Obata T, Ota K, Sasaki T, Ito T
The Journal of biological chemistry 2003 Jun 6;278(23):20457-60

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Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.

Saelens X, Kalai M, Vandenabeele P
The Journal of biological chemistry 2001 Nov 9;276(45):41620-8