DPABH-14336

antibody from Creative Diagnostics

Targeting: MMP17 MT4-MMP

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-14336

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-14336, RRID:AB_2525250

Product name

Rabbit Anti-Human MMP17 Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.