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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN1673186 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Suppressor of Cytokine Signaling 3 (SOCS3) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence in the middle region of human SOCS3, identical to the related mouse sequence, different from the related rat sequence by one amino acid.Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis.
Chen Z, Laurence A, Kanno Y, Pacher-Zavisin M, Zhu BM, Tato C, Yoshimura A, Hennighausen L, O'Shea JJ
Proceedings of the National Academy of Sciences of the United States of America 2006 May 23;103(21):8137-42
Proceedings of the National Academy of Sciences of the United States of America 2006 May 23;103(21):8137-42
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.
Babon JJ, McManus EJ, Yao S, DeSouza DP, Mielke LA, Sprigg NS, Willson TA, Hilton DJ, Nicola NA, Baca M, Nicholson SE, Norton RS
Molecular cell 2006 Apr 21;22(2):205-16
Molecular cell 2006 Apr 21;22(2):205-16
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis.
Jo D, Liu D, Yao S, Collins RD, Hawiger J
Nature medicine 2005 Aug;11(8):892-8
Nature medicine 2005 Aug;11(8):892-8
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