ABIN967669

antibody from antibodies-online

Targeting: H2AX H2AFX

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN967669

Provider

antibodies-online

Product name

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody

Antibody type

Monoclonal

Antigen

Phosphorylated Human H2AX Peptide

Reactivity

Human, Mouse

Host

Mouse

Isotype

IgG

Antibody clone number

N1-431

Vial size

0.1 mg

Concentration

0.5 mg/ml

Storage

Store undiluted at 4°C.

References

Submitted references

Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

Kuo LJ, Yang LX
In vivo (Athens, Greece) 2008 May-Jun;22(3):305-9

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H2AX: the histone guardian of the genome.

Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A
DNA repair 2004 Aug-Sep;3(8-9):959-67

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks.

Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ
The Journal of biological chemistry 2001 Nov 9;276(45):42462-7

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Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139.

Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM
The Journal of biological chemistry 2000 Mar 31;275(13):9390-5

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.

Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM
The Journal of biological chemistry 1998 Mar 6;273(10):5858-68