Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- AF1970 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Thioredoxin-1 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Thioredoxin-1 in direct ELISAs and Western blots. In direct ELISAs, less than 25% cross-reactivity with recombinant mouse Thioredoxin-1 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor.
Thioredoxin-related mechanisms in hyperoxic lung injury in mice.
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
Ito T, Yamakuchi M, Lowenstein CJ
The Journal of biological chemistry 2011 Apr 1;286(13):11179-84
The Journal of biological chemistry 2011 Apr 1;286(13):11179-84
Thioredoxin-related mechanisms in hyperoxic lung injury in mice.
Tipple TE, Welty SE, Rogers LK, Hansen TN, Choi YE, Kehrer JP, Smith CV
American journal of respiratory cell and molecular biology 2007 Oct;37(4):405-13
American journal of respiratory cell and molecular biology 2007 Oct;37(4):405-13
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
Mitchell DA, Morton SU, Fernhoff NB, Marletta MA
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 10;104(28):11609-14
Proceedings of the National Academy of Sciences of the United States of America 2007 Jul 10;104(28):11609-14
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Thioredoxin-1 by Simple WesternTM. Detection of Human Thioredoxin-1 by Simple WesternTM.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Thioredoxin-1 by Western Blot. Detection of Human Thioredoxin-1 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Thioredoxin-1 in Human Breast Cancer Tissue. Thioredoxin-1 in Human Breast Cancer Tissue.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Thioredoxin-1 in Human Breast Cancer Tissue. Thioredoxin-1 in Human Breast Cancer Tissue.