Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN356853 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Thioredoxin (TXN) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Truncated thioredoxin (Trx80) induces differentiation of human CD14+ monocytes into a novel cell type (TAMs) via activation of the MAP kinases p38, ERK, and JNK.
Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB.
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.
Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein.
Pekkari K, Goodarzi MT, Scheynius A, Holmgren A, Avila-CariƱo J
Blood 2005 Feb 15;105(4):1598-605
Blood 2005 Feb 15;105(4):1598-605
Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB.
Li Y, Liu W, Xing G, Tian C, Zhu Y, He F
Cellular signalling 2005 Aug;17(8):985-96
Cellular signalling 2005 Aug;17(8):985-96
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.
Hwang CY, Ryu YS, Chung MS, Kim KD, Park SS, Chae SK, Chae HZ, Kwon KS
Oncogene 2004 Nov 25;23(55):8868-75
Oncogene 2004 Nov 25;23(55):8868-75
Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein.
Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT
The Journal of biological chemistry 2004 Jul 16;279(29):30369-74
The Journal of biological chemistry 2004 Jul 16;279(29):30369-74
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