ABIN197351

antibody from antibodies-online

Targeting: CDKN1B KIP1, P27KIP1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197351

Provider

antibodies-online

Product name

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (Ser10) antibody

Antibody type

Polyclonal

Description

Immunoaffinity Chromatography.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Ser10

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions.

McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF
Molecular and cellular biology 2003 Jan;23(1):216-28

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CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis.

Connor MK, Kotchetkov R, Cariou S, Resch A, Lupetti R, Beniston RG, Melchior F, Hengst L, Slingerland JM
Molecular biology of the cell 2003 Jan;14(1):201-13

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Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.

Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ
The Journal of biological chemistry 2002 Sep 6;277(36):32413-6

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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG
The EMBO journal 2002 Jul 1;21(13):3390-401