ABIN966734

antibody from antibodies-online

Targeting: CDKN1B KIP1, P27KIP1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966734

Provider

antibodies-online

Product name

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-SP-P-S).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 µg

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.

Le XF, Claret FX, Lammayot A, Tian L, Deshpande D, LaPushin R, Tari AM, Bast RC Jr
The Journal of biological chemistry 2003 Jun 27;278(26):23441-50

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions.

McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF
Molecular and cellular biology 2003 Jan;23(1):216-28

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CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis.

Connor MK, Kotchetkov R, Cariou S, Resch A, Lupetti R, Beniston RG, Melchior F, Hengst L, Slingerland JM
Molecular biology of the cell 2003 Jan;14(1):201-13

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Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.

Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ
The Journal of biological chemistry 2002 Sep 6;277(36):32413-6

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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG
The EMBO journal 2002 Jul 1;21(13):3390-401