ABIN1003083
antibody from antibodies-online
Targeting: DDX58
DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1003083 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) antibody
- Antibody type
- Polyclonal
- Antigen
- RIG-1 antibody was raised against human GST-tagged RIG-1 protein.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Pathogen recognition and innate immunity.
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
Triggering the interferon antiviral response through an IKK-related pathway.
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
Akira S, Uematsu S, Takeuchi O
Cell 2006 Feb 24;124(4):783-801
Cell 2006 Feb 24;124(4):783-801
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T
Nature immunology 2004 Jul;5(7):730-7
Nature immunology 2004 Jul;5(7):730-7
Triggering the interferon antiviral response through an IKK-related pathway.
Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J
Science (New York, N.Y.) 2003 May 16;300(5622):1148-51
Science (New York, N.Y.) 2003 May 16;300(5622):1148-51
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA
Nature 2001 Oct 18;413(6857):732-8
Nature 2001 Oct 18;413(6857):732-8
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