orb151334

antibody from Biorbyt

Targeting: KDELR1 ERD2, ERD2.1, HDEL

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

orb151334

Provider

Biorbyt

Product name

KDEL antibody (ATTO-488)

Antibody type

Polyclonal

Description

Rabbit polyclonal to KDEL (ATTO-488). The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER..

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Green dye

Vial size

200 μg

Concentration

1 mg/ml

Storage

Store at 2-8°C and -20°C for one year. (Shipped on ice packs)