orb97711

antibody from Biorbyt

Targeting: IL10 CSIF, IL-10, IL10A, TGIF

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

orb97711

Provider

Biorbyt

Product name

IL10 antibody

Antibody type

Monoclonal

Description

Rat monoclonal to IL10.IL-10 is a cytokine produced primarily by monocytesand to a lesser extent by lymphocytes. This cytokinehas pleiotrophic effects in immunoregulation and inflammation. It down-regulates the expression of Th1cytokines, MHC class II Ags, and costimulatory moleculeson macrophages. It also enhances B-cell survival,proliferation, and antibody production. This cytokinecan block NF-kappa B activity, and is involved in theregulation of the JAK-STAT signalling pathway. Knockoutstudies in mice suggested the function of this cytokine asan essential immunoregulator in the intestinal tract.

Host

Rat

Conjugate

Unconjugated

Isotype

IgG

Vial size

500 μg

Storage

Store at-20°C.