501501

antibody from BioLegend

Targeting: IL10 CSIF, IL-10, IL10A, TGIF

ELISA (Data presented on provider website)

Other assay (Recommended by provider)

Antibody Data

Product number

501501

Provider

BioLegend

Proper citation

BioLegend Cat#501501, RRID:AB_315177

Product name

Biotin anti-human IL-10

Antibody type

Monoclonal

Antigen

COS - expressed, recombinant human IL-10

Description

IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production. The JES3-12G8 antibody reacts with human and viral interleukin-10 (IL-10). The JES3-12G8 antibody can neutralize the bioactivity of natural or recombinant IL-10.

Reactivity

Human

Host

Rat

Conjugate

Biotin

Isotype

IgG

Vial size

50 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C. Do not freeze.