Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN307102 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (pTyr529) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human, Mouse, Rat, Chicken/Avian
- Host
- Rabbit
- Epitope
- pTyr529
- Antibody clone number
- Polyclonal
- Vial size
- 100 μL
- Storage
- -80°C
Submitted references Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells.
Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.
Reelin activates SRC family tyrosine kinases in neurons.
Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.
Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton.
Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity.
Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.
Src tyrosine kinase is a novel direct effector of G proteins.
Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1.
Gil-Henn H, Elson A
The Journal of biological chemistry 2003 May 2;278(18):15579-86
The Journal of biological chemistry 2003 May 2;278(18):15579-86
Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.
Pankov R, Cukierman E, Clark K, Matsumoto K, Hahn C, Poulin B, Yamada KM
The Journal of biological chemistry 2003 May 16;278(20):18671-81
The Journal of biological chemistry 2003 May 16;278(20):18671-81
Reelin activates SRC family tyrosine kinases in neurons.
Bock HH, Herz J
Current biology : CB 2003 Jan 8;13(1):18-26
Current biology : CB 2003 Jan 8;13(1):18-26
Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.
Lacalle RA, Mira E, Gomez-Mouton C, Jimenez-Baranda S, Martinez-A C, Manes S
The Journal of cell biology 2002 Apr 15;157(2):277-89
The Journal of cell biology 2002 Apr 15;157(2):277-89
Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton.
Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ
The Journal of cell biology 2002 Apr 15;157(2):265-75
The Journal of cell biology 2002 Apr 15;157(2):265-75
Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity.
Manzerra P, Behrens MM, Canzoniero LM, Wang XQ, Heidinger V, Ichinose T, Yu SP, Choi DW
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11055-61
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11055-61
Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.
Cheng A, Bal GS, Kennedy BP, Tremblay ML
The Journal of biological chemistry 2001 Jul 13;276(28):25848-55
The Journal of biological chemistry 2001 Jul 13;276(28):25848-55
Src tyrosine kinase is a novel direct effector of G proteins.
Ma YC, Huang J, Ali S, Lowry W, Huang XY
Cell 2000 Sep 1;102(5):635-46
Cell 2000 Sep 1;102(5):635-46
Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1.
Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Price RL, Schaefer E, Yager K
The Journal of clinical investigation 2000 Apr;105(7):875-86
The Journal of clinical investigation 2000 Apr;105(7):875-86
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis using Src [pY529] antibody on CEF cells untransfected (1) or transfeceted with wild-type human Src (2-5). Antibody was incubated prior to use with no peptide (1,2), non- phosphorylated immunogen peptide (3), generic phosphotyrosine containing peptide (4), or phosphorylated immunogen peptide (5)., Chicken, Frog Fyn and Yes (92% homologous) were not tested for crossreactivity.