NBP2-47751AF700

antibody from Novus Biologicals

Targeting: TLR4 ARMD10, CD284, hToll, TLR-4

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-47751AF700

Provider

Novus Biologicals

Product name

Mouse Monoclonal TLR4 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Rat, Canine, Guinea Pig, Porcine, Simian

Host

Mouse

Conjugate

Near infrared dye

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.