ABIN493502

antibody from antibodies-online

Targeting: TLR4 ARMD10, CD284, hToll, TLR-4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN493502

Provider

antibodies-online

Product name

anti-Toll-Like Receptor 4 (TLR4) (C-Term), (AA 976-998) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide selected from Human TLR4 corresponding to amino acids 976-998 (dgk swn peg tvg tgc nwq eat si) near the C-terminal end of the protein.

Description

Affinity Chromatography using immobilized antigen

Reactivity

Human

Host

Rabbit

Epitope

C-Term,AA 976-998

Isotype

IgG

Vial size

0.1 mg

Concentration

0.66-0.80

Storage

Store the antibody undiluted (in aliquots) at-20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion.

Hua F, Ma J, Ha T, Xia Y, Kelley J, Williams DL, Kao RL, Browder IW, Schweitzer JB, Kalbfleisch JH, Li C
Journal of neuroimmunology 2007 Oct;190(1-2):101-11

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Toll-like receptor 4 deficiency causes pulmonary emphysema.

Zhang X, Shan P, Jiang G, Cohn L, Lee PJ
The Journal of clinical investigation 2006 Nov;116(11):3050-9

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT
The Journal of experimental medicine 2003 Oct 6;198(7):1043-55

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.

Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T
Nature immunology 2003 Feb;4(2):161-7

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TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

Oshiumi H, Sasai M, Shida K, Fujita T, Matsumoto M, Seya T
The Journal of biological chemistry 2003 Dec 12;278(50):49751-62