Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362230 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ezrin (EZR) (pThr567) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr567 (Y-K-T (p) -L-R) derived from Human Ezrin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr567
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell.
Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation.
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin.
Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.
Zhou R, Zhu L, Kodani A, Hauser P, Yao X, Forte JG
Journal of cell science 2005 Oct 1;118(Pt 19):4381-91
Journal of cell science 2005 Oct 1;118(Pt 19):4381-91
Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation.
Shiue H, Musch MW, Wang Y, Chang EB, Turner JR
The Journal of biological chemistry 2005 Jan 14;280(2):1688-95
The Journal of biological chemistry 2005 Jan 14;280(2):1688-95
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin.
Fievet BT, Gautreau A, Roy C, Del Maestro L, Mangeat P, Louvard D, Arpin M
The Journal of cell biology 2004 Mar 1;164(5):653-9
The Journal of cell biology 2004 Mar 1;164(5):653-9
Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.
Zhao H, Shiue H, Palkon S, Wang Y, Cullinan P, Burkhardt JK, Musch MW, Chang EB, Turner JR
Proceedings of the National Academy of Sciences of the United States of America 2004 Jun 22;101(25):9485-90
Proceedings of the National Academy of Sciences of the United States of America 2004 Jun 22;101(25):9485-90
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