FAB1263P

antibody from Novus Biologicals

Targeting: PDGFRB CD140b, JTK12, PDGFR, PDGFR1

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

FAB1263P

Provider

Novus Biologicals

Product name

Mouse Monoclonal PDGF R beta Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from ascites. Detects human PDGF R beta in Western blots. Specificity has been confirmed in binding studies using several different cell lines (1, 2) and by its ability to immunoprecipitate PDGF R beta-subunit complexed with 125I-PDGF-BB (3). It does not recognize the PDGF R alpha-subunit. Detects the PDGF R beta-subunit of human and primate species (monkey and baboon) but not the rat or mouse receptors. Its ability to bind to receptors from other species has not been tested.

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.

References

Submitted references

Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle.

Xu S, Chan RWS, Ng EHY, Yeung WSB
Experimental cell research 2017 Jan 1;350(1):184-189

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Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.

To C, Farnsworth RH, Vail ME, Chheang C, Gargett CE, Murone C, Llerena C, Major AT, Scott AM, Janes PW, Lackmann M
PloS one 2014;9(11):e112106

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Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.

Norton KA, Han Z, Popel AS, Pandey NB
OncoTargets and therapy 2014;7:1571-82

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Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes.

Guijarro-Muñoz I, Compte M, Álvarez-Cienfuegos A, Álvarez-Vallina L, Sanz L
The Journal of biological chemistry 2014 Jan 24;289(4):2457-68

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Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies.

Frassanito MA, Rao L, Moschetta M, Ria R, Di Marzo L, De Luisi A, Racanelli V, Catacchio I, Berardi S, Basile A, Menu E, Ruggieri S, Nico B, Ribatti D, Fumarulo R, Dammacco F, Vanderkerken K, Vacca A
Leukemia 2014 Apr;28(4):904-16

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Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.

Albert R, Veréb Z, Csomós K, Moe MC, Johnsen EO, Olstad OK, Nicolaissen B, Rajnavölgyi E, Fésüs L, Berta A, Petrovski G
PloS one 2012;7(10):e47187

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The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis.

Guijarro-Muñoz I, Cuesta AM, Alvarez-Cienfuegos A, Geng JG, Alvarez-Vallina L, Sanz L
Experimental cell research 2012 Feb 15;318(4):371-8

Flow cytometry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Detection of PDGF R beta in MG-63 Human Cell Line by Flow Cytometry. MG-63 human osteosarcoma cell line was stained with Mouse Anti-Human PDGF R beta PE-conjugated Monoclonal Antibody (Catalog # FAB1263P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.