ABIN362448

antibody from antibodies-online

Targeting: EIF4B

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362448

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 4B (EIF4B) (pSer422) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer422 (T-G-S (p) -E-S) derived from Human eIF4B. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pSer422

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Regulation of translation initiation by FRAP/mTOR.

Gingras AC, Raught B, Sonenberg N
Genes & development 2001 Apr 1;15(7):807-26

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Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.

Landry J, Chrétien P, Lambert H, Hickey E, Weber LA
The Journal of cell biology 1989 Jul;109(1):7-15

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Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification.

Duncan R, Hershey JW
The Journal of biological chemistry 1985 May 10;260(9):5493-7