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- Antibody Data
- Antigen structure
- References [38]
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- Validations
- Immunohistochemistry [1]
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- Product number
- 600-401-106S - Provider product page
- Provider
- Rockland Immunochemicals, Inc.
- Proper citation
- Rockland Cat#600-401-106S, RRID:AB_11183330
- Product name
- Anti-Collagen Type IV (RABBIT) Antibody - 600-401-106S
- Antibody type
- Polyclonal
- Vial size
- 25 µl
Submitted references ROCK 1 and 2 affect the spatial architecture of 3D spheroids derived from human corneal stromal fibroblasts in different manners.
Comparison of the Drug-Induced Efficacies between Omidenepag Isopropyl, an EP2 Agonist and PGF2α toward TGF-β2-Modulated Human Trabecular Meshwork (HTM) Cells.
Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis.
Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption.
The latent dedifferentiation capacity of newt limb muscles is unleashed by a combination of metamorphosis and body growth.
Deletion of Myeloid Interferon Regulatory Factor 4 (Irf4) in Mouse Model Protects against Kidney Fibrosis after Ischemic Injury by Decreased Macrophage Recruitment and Activation.
The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1(+) hematoendothelial progenitors.
Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type 2 Diabetic Nephropathy.
Prostaglandin F2α agonist-induced suppression of 3T3-L1 cell adipogenesis affects spatial formation of extra-cellular matrix.
Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
Effect of sex differences in treatment response to angioplasty in a murine arteriovenous fistula model.
Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis.
A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro.
Histone demethylase UTX is a therapeutic target for diabetic kidney disease.
HIF2A-LOX Pathway Promotes Fibrotic Tissue Remodeling in Thyroid-Associated Orbitopathy.
Myeloid Zinc Finger 1 (MZF1) Maintains the Mesenchymal Phenotype by Down-regulating IGF1R/p38 MAPK/ERα Signaling Pathway in High-level MZF1-expressing TNBC cells.
A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells.
Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.
Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells.
In Situ Imaging of Tissue Remodeling with Collagen Hybridizing Peptides.
Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts.
Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation.
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth.
3-D adipocyte differentiation and peri-adipocyte collagen turnover.
FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney.
AMP-activated protein kinase regulates intraocular pressure, extracellular matrix, and cytoskeleton in trabecular meshwork.
Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72.
Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebrates.
Skin shedding and tissue regeneration in African spiny mice (Acomys).
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshwork.
The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.
Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.
Collagen IV synthesis is restricted to the enteroendocrine pathway during multilineage differentiation of human colorectal epithelial stem cells.
Ida Y, Umetsu A, Furuhashi M, Watanabe M, Tsugeno Y, Suzuki S, Hikage F, Ohguro H
Scientific reports 2022 May 6;12(1):7419
Scientific reports 2022 May 6;12(1):7419
Comparison of the Drug-Induced Efficacies between Omidenepag Isopropyl, an EP2 Agonist and PGF2α toward TGF-β2-Modulated Human Trabecular Meshwork (HTM) Cells.
Suzuki S, Furuhashi M, Tsugeno Y, Umetsu A, Ida Y, Hikage F, Ohguro H, Watanabe M
Journal of clinical medicine 2022 Mar 16;11(6)
Journal of clinical medicine 2022 Mar 16;11(6)
Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis.
Sasaki K, Terker AS, Tang J, Cao S, Arroyo JP, Niu A, Wang S, Fan X, Zhang Y, Bennett SR, Zhang MZ, Harris RC
JCI insight 2022 Feb 22;7(4)
JCI insight 2022 Feb 22;7(4)
Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption.
Hu C, Beebe K, Hernandez EJ, Lazaro-Guevara JM, Revelo MP, Huang Y, Maschek JA, Cox JE, Kohan DE
American journal of physiology. Renal physiology 2022 Feb 1;322(2):F175-F192
American journal of physiology. Renal physiology 2022 Feb 1;322(2):F175-F192
The latent dedifferentiation capacity of newt limb muscles is unleashed by a combination of metamorphosis and body growth.
Yu ZY, Shiga S, Casco-Robles MM, Takeshima K, Maruo F, Chiba C
Scientific reports 2022 Aug 1;12(1):11653
Scientific reports 2022 Aug 1;12(1):11653
Deletion of Myeloid Interferon Regulatory Factor 4 (Irf4) in Mouse Model Protects against Kidney Fibrosis after Ischemic Injury by Decreased Macrophage Recruitment and Activation.
Sasaki K, Terker AS, Pan Y, Li Z, Cao S, Wang Y, Niu A, Wang S, Fan X, Zhang MZ, Harris RC
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1037-1052
Journal of the American Society of Nephrology : JASN 2021 May 3;32(5):1037-1052
The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1(+) hematoendothelial progenitors.
Nandadasa S, O'Donnell A, Murao A, Yamaguchi Y, Midura RJ, Olson L, Apte SS
Matrix biology : journal of the International Society for Matrix Biology 2021 Mar;97:40-57
Matrix biology : journal of the International Society for Matrix Biology 2021 Mar;97:40-57
Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type 2 Diabetic Nephropathy.
Li Y, Pan Y, Cao S, Sasaki K, Wang Y, Niu A, Fan X, Wang S, Zhang MZ, Harris RC
Diabetes 2021 Feb;70(2):562-576
Diabetes 2021 Feb;70(2):562-576
Prostaglandin F2α agonist-induced suppression of 3T3-L1 cell adipogenesis affects spatial formation of extra-cellular matrix.
Ida Y, Hikage F, Itoh K, Ida H, Ohguro H
Scientific reports 2020 May 14;10(1):7958
Scientific reports 2020 May 14;10(1):7958
Asynchronous mixing of kidney progenitor cells potentiates nephrogenesis in organoids.
Kumar Gupta A, Sarkar P, Wertheim JA, Pan X, Carroll TJ, Oxburgh L
Communications biology 2020 May 11;3(1):231
Communications biology 2020 May 11;3(1):231
Effect of sex differences in treatment response to angioplasty in a murine arteriovenous fistula model.
Cai C, Zhao C, Kilari S, Sharma A, Singh AK, Simeon ML, Misra A, Li Y, Misra S
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F565-F575
American journal of physiology. Renal physiology 2020 Mar 1;318(3):F565-F575
Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis.
Liu S, Huang Z, Tang A, Wu X, Aube J, Xu L, Xing C, Huang Y
Clinical science (London, England : 1979) 2020 Jun 26;134(12):1433-1448
Clinical science (London, England : 1979) 2020 Jun 26;134(12):1433-1448
A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro.
Keller F, Bruch R, Schneider R, Meier-Hubberten J, Hafner M, Rudolf R
Cells 2020 Aug 13;9(8)
Cells 2020 Aug 13;9(8)
Histone demethylase UTX is a therapeutic target for diabetic kidney disease.
Chen H, Huang Y, Zhu X, Liu C, Yuan Y, Su H, Zhang C, Liu C, Xiong M, Qu Y, Yun P, Zheng L, Huang K
The Journal of physiology 2019 Mar;597(6):1643-1660
The Journal of physiology 2019 Mar;597(6):1643-1660
HIF2A-LOX Pathway Promotes Fibrotic Tissue Remodeling in Thyroid-Associated Orbitopathy.
Hikage F, Atkins S, Kahana A, Smith TJ, Chun TH
Endocrinology 2019 Jan 1;160(1):20-35
Endocrinology 2019 Jan 1;160(1):20-35
Myeloid Zinc Finger 1 (MZF1) Maintains the Mesenchymal Phenotype by Down-regulating IGF1R/p38 MAPK/ERα Signaling Pathway in High-level MZF1-expressing TNBC cells.
Yue CH, Liu JY, Chi CS, Hu CW, Tan KT, Huang FM, Pan YR, Lin KI, Lee CJ
Anticancer research 2019 Aug;39(8):4149-4164
Anticancer research 2019 Aug;39(8):4149-4164
A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells.
Klicks J, Maßlo C, Kluth A, Rudolf R, Hafner M
BMC cancer 2019 Apr 29;19(1):402
BMC cancer 2019 Apr 29;19(1):402
Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.
Li Y, Chung S, Li Z, Overstreet JM, Gagnon L, Grouix B, Leduc M, Laurin P, Zhang MZ, Harris RC
JCI insight 2018 May 17;3(10)
JCI insight 2018 May 17;3(10)
Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells.
Akama T, Chun TH
The Journal of biological chemistry 2018 Apr 27;293(17):6603-6610
The Journal of biological chemistry 2018 Apr 27;293(17):6603-6610
In Situ Imaging of Tissue Remodeling with Collagen Hybridizing Peptides.
Hwang J, Huang Y, Burwell TJ, Peterson NC, Connor J, Weiss SJ, Yu SM, Li Y
ACS nano 2017 Oct 24;11(10):9825-9835
ACS nano 2017 Oct 24;11(10):9825-9835
Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy.
Wang X, Yao B, Wang Y, Fan X, Wang S, Niu A, Yang H, Fogo A, Zhang MZ, Harris RC
Diabetes 2017 Feb;66(2):494-504
Diabetes 2017 Feb;66(2):494-504
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Ma S, Sun R, Jiang B, Gao J, Deng W, Liu P, He R, Cui J, Ji M, Yi W, Yang P, Wu X, Xiong Y, Qiu Z, Ye D, Guan KL
Molecular and cellular biology 2017 Apr 15;37(8)
Molecular and cellular biology 2017 Apr 15;37(8)
Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.
Mi Z, Halfter W, Abrahamson EE, Klunk WE, Mathis CA, Mufson EJ, Ikonomovic MD
Journal of neuropathology and experimental neurology 2016 Sep;75(9):868-76
Journal of neuropathology and experimental neurology 2016 Sep;75(9):868-76
Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.
Dubail J, Vasudevan D, Wang LW, Earp SE, Jenkins MW, Haltiwanger RS, Apte SS
Scientific reports 2016 Sep 30;6:33974
Scientific reports 2016 Sep 30;6:33974
A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts.
Tanaka HV, Ng NCY, Yang Yu Z, Casco-Robles MM, Maruo F, Tsonis PA, Chiba C
Nature communications 2016 Mar 30;7:11069
Nature communications 2016 Mar 30;7:11069
Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation.
Sharmin S, Taguchi A, Kaku Y, Yoshimura Y, Ohmori T, Sakuma T, Mukoyama M, Yamamoto T, Kurihara H, Nishinakamura R
Journal of the American Society of Nephrology : JASN 2016 Jun;27(6):1778-91
Journal of the American Society of Nephrology : JASN 2016 Jun;27(6):1778-91
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth.
Ma S, Jiang B, Deng W, Gu ZK, Wu FZ, Li T, Xia Y, Yang H, Ye D, Xiong Y, Guan KL
Oncotarget 2015 Apr 20;6(11):8606-20
Oncotarget 2015 Apr 20;6(11):8606-20
3-D adipocyte differentiation and peri-adipocyte collagen turnover.
Chun TH, Inoue M
Methods in enzymology 2014;538:15-34
Methods in enzymology 2014;538:15-34
FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney.
Fetting JL, Guay JA, Karolak MJ, Iozzo RV, Adams DC, Maridas DE, Brown AC, Oxburgh L
Development (Cambridge, England) 2014 Jan;141(1):17-27
Development (Cambridge, England) 2014 Jan;141(1):17-27
AMP-activated protein kinase regulates intraocular pressure, extracellular matrix, and cytoskeleton in trabecular meshwork.
Chatterjee A, Villarreal G Jr, Oh DJ, Kang MH, Rhee DJ
Investigative ophthalmology & visual science 2014 Apr 8;55(5):3127-39
Investigative ophthalmology & visual science 2014 Apr 8;55(5):3127-39
Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72.
Murray ME, Bieniek KF, Banks Greenberg M, DeJesus-Hernandez M, Rutherford NJ, van Blitterswijk M, Niemantsverdriet E, Ash PE, Gendron TF, Kouri N, Baker M, Goodman IJ, Petrucelli L, Rademakers R, Dickson DW
Acta neuropathologica 2013 Oct;126(4):545-54
Acta neuropathologica 2013 Oct;126(4):545-54
Skin regeneration in adult axolotls: a blueprint for scar-free healing in vertebrates.
Seifert AW, Monaghan JR, Voss SR, Maden M
PloS one 2012;7(4):e32875
PloS one 2012;7(4):e32875
Skin shedding and tissue regeneration in African spiny mice (Acomys).
Seifert AW, Kiama SG, Seifert MG, Goheen JR, Palmer TM, Maden M
Nature 2012 Sep 27;489(7417):561-5
Nature 2012 Sep 27;489(7417):561-5
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW
Genes & development 2012 Sep 15;26(18):2038-49
Genes & development 2012 Sep 15;26(18):2038-49
Coordinated regulation of extracellular matrix synthesis by the microRNA-29 family in the trabecular meshwork.
Villarreal G Jr, Oh DJ, Kang MH, Rhee DJ
Investigative ophthalmology & visual science 2011 May 1;52(6):3391-7
Investigative ophthalmology & visual science 2011 May 1;52(6):3391-7
The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.
Wiessner C, Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jun 22;31(25):9323-31
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jun 22;31(25):9323-31
Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.
Morrison JI, Lööf S, He P, Simon A
The Journal of cell biology 2006 Jan 30;172(3):433-40
The Journal of cell biology 2006 Jan 30;172(3):433-40
Collagen IV synthesis is restricted to the enteroendocrine pathway during multilineage differentiation of human colorectal epithelial stem cells.
Kirkland SC, Henderson K
Journal of cell science 2001 Jun;114(Pt 11):2055-64
Journal of cell science 2001 Jun;114(Pt 11):2055-64
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Supportive validation
- Submitted by
- Rockland Immunochemicals, Inc. (provider)
- Main image
- Experimental details
- Rockland anti collagen IV antibody (600-401-106 Lot 25440, 1:400, 45 min RT) showed strong staining in FFPE sections of human kidney (Left) with strong red staining observed in glomeruli; and liver (Right) with strong staining in sinusoids. Staining for both tissues was consistent with a basement membrane distribution. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA
- Validation comment
- Immunohistochemistry
