ABIN1002687

antibody from antibodies-online

Targeting: SP110 IFI41, IFI75

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1002687

Provider

antibodies-online

Product name

anti-SP110 Nuclear Body Protein (SP110) (N-Term) antibody

Antibody type

Polyclonal

Antigen

IPR1 antibody was raised in rabbits against a 16 amino acid peptide near the amino terminus of the human IPR1.

Description

Affinity chromatography purified via peptide column.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

N-Term

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.

Tosh K, Campbell SJ, Fielding K, Sillah J, Bah B, Gustafson P, Manneh K, Lisse I, Sirugo G, Bennett S, Aaby P, McAdam KP, Bah-Sow O, Lienhardt C, Kramnik I, Hill AV
Proceedings of the National Academy of Sciences of the United States of America 2006 Jul 5;103(27):10364-8

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Ipr1 gene mediates innate immunity to tuberculosis.

Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, Higgins DE, Daly MJ, Bloom BR, Kramnik I
Nature 2005 Apr 7;434(7034):767-72

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Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator.

Bloch DB, Nakajima A, Gulick T, Chiche JD, Orth D, de La Monte SM, Bloch KD
Molecular and cellular biology 2000 Aug;20(16):6138-46