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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- orb99101 - Provider product page
- Provider
- Biorbyt
- Product name
- SUR1 and SUR2B antibody
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal to SUR1 and SUR2B.Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea classof antidiabetic drugs whose mechanism of action is topromote insulin release from pancreatic beta cells. Morespecifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2) .The association of four Kir6.x and four SUR subunits forman ion conducting channel commonly referred to as theKATP channel.The primary function of the sulfonylurea receptor is to senseintracellular levels of the nucleotides ATP and ADP and inresponse facilitate the open or closing its associated Kir6.xpotassium channel. Hence the KATPchannel monitors the energy balance within the cell .
- Reactivity
- Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- S323A-31
- Vial size
- 100 μg
- Concentration
- 1mg/mL
- Storage
- Store at -20°C.
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