Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB600-1279 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1279, RRID:AB_10001544
- Product name
- Mouse Monoclonal p73 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 uL
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma.
Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding.
Cam M, Charan M, Welker AM, Dravid P, Studebaker AW, Leonard JR, Pierson CR, Nakano I, Beattie CE, Hwang EI, Kambhampati M, Nazarian J, Finlay JL, Cam H
Neuro-oncology 2020 Mar 5;22(3):345-356
Neuro-oncology 2020 Mar 5;22(3):345-356
Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding.
King KE, Reddi DM, Ponnamperuma RM, Gerdes M, Weinberg WC
Molecular carcinogenesis 2014 Sep;53(9):698-710
Molecular carcinogenesis 2014 Sep;53(9):698-710
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Western Blot: p73 Antibody (ER-15) [NB600-1279] - Altered expression of proteins upon cell treatment demonstrates antibody specificity. Western blot using p73 alpha/beta Monoclonal Antibody, shows increased levels of p73 alpha/beta in MCF7 cell line upon doxorubicin treatment.