Antibody data
- Antibody Data
- Antigen structure
- References [63]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Other assay [3]
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Validation data
Reference
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- Product number
- MA5-12969 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- S100 Monoclonal Antibody (4C4.9)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-12969 targets S100 Protein in IHC (P), ICC/IF and WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples.
- Antibody clone number
- 4C4.9
- Concentration
- 0.2 mg/mL
Submitted references Erythropoietin promotes M2 macrophage phagocytosis of Schwann cells in peripheral nerve injury.
SUMOylation regulates Rb hyperphosphorylation and inactivation in uveal melanoma.
Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders.
H3.3 K36M Mutation as a Clinical Diagnosis Method of Suspected Chondroblastoma Cases.
Side-to-side supercharging nerve allograft enhances neurotrophic potential.
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.
The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain.
Nerve Tissue Prefabrication Inside the Rat Femoral Bone: Does It Work?
Searching for proprioceptors in human facial muscles.
The Ewing's Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature.
A challenging case of ocular melanoma.
CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma.
RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development.
ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin.
Comparison of the cellular composition of two different chondrocyte-seeded biomaterials and the results of their transplantation in humans.
Neurogenic contraction induced by the antiarrhythmic compound, AVE 0118, in rat small mesenteric arteries.
A rare malignancy of the parotid gland in a 13-year-old Taiwanese boy: case report of a mammary analogue secretory carcinoma of the salivary gland with molecular study.
Neurophysiological and immunohistochemical studies of IgG anti-GM1 monoclonal antibody on neuromuscular transmission: effects in rat neuromuscular junctions.
Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma.
Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.
The sensory innervation of the human pharynx: searching for mechanoreceptors.
Concha bullosa surgery and the distribution of human olfactory neuroepithelium.
Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors.
Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Langerhans cells in odontogenic epithelia of odontogenic fibromas.
Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature.
Histological assessment of mechanoreceptors in Achilles allografts after anterior cruciate ligament reconstruction.
Evidence of nestin-positive cells in the human cutaneus Meissner and Pacinian corpuscles.
Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis.
Pigmented paraganglioma of the kidney: a case report.
Cotyledonoid leiomyoma of uterus: a case report.
Intraglomerular crescentic metastases of malignant melanoma.
Papillary urothelial carcinoma of the bladder with exuberant pseudosarcomatous stromal reaction following radiation therapy.
Copy number alterations and expression profiles of candidate genes in a pulmonary inflammatory myofibroblastic tumor.
Extracellular matrix degradation and reduced neural density in children with intrinsic ureteropelvic junction obstruction.
Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles.
Uterine carcinosarcoma metastatic to the lung as large-cell neuroendocrine carcinoma with synchronous sarcoid granulomatosis.
Rhabdomyosarcoma arising in a mature cystic teratoma with contralateral serous carcinoma: case report and review of the literature.
Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats.
Primary choroid plexus papilloma of the sacral nerve roots.
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
Cutaneous metastases of malignant melanoma--how difficult can it be?
The coexistence of invasive ductal carcinoma and malignant phyllodes tumor with liposarcomatous and chondrosarcomatous differentiation in the same breast in a post-osteosarcoma case.
Metastatic malignant melanoma of the uterine cervix: first diagnosed on liquid-based cytology.
Epithelioid leiomyosarcoma with rhabdoid features.
Myointimoma of the glans penis.
Fine needle aspiration cytology of inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: a case report and review of the literature.
Atherosclerosis research from past to present--on the track of two pathologists with opposing views, Carl von Rokitansky and Rudolf Virchow.
Low grade myofibroblastic sarcoma of tongue: a case report.
Reduction of GFAP induced by long dark rearing is not restricted to visual cortex.
Recurrent intracranial hemangiopericytoma with multiple metastases.
Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients.
Recurrent solitary fibrous tumour in the cerebellopontine angle.
Analysis of prognostic and immunohistochemical factors in gastrointestinal stromal tumors with malignant potential.
Pulmonary large cell carcinoma with rhabdoid phenotype.
Mazabraud's syndrome: intramuscular myxoma associated with fibrous dysplasia.
Spindle cell lipoma in an intramuscular lipoma.
Synchronous primary adenocarcinoma and gastrointestinal stromal tumor in the stomach: a report of two cases.
Malignant gastrointestinal stromal tumor of the gallbladder.
Collagenous fibroma (desmoplastic fibroblastoma).
Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study.
Concomitant distribution shift of glial GABA transporter and S100 calcium-binding proteins in the rat retina after kainate-induced excitotoxic injury.
Two intraligamentary lipomatous tumors with immunohistochemical features.
Govindappa PK, Elfar JC
Cell death & disease 2022 Mar 16;13(3):245
Cell death & disease 2022 Mar 16;13(3):245
SUMOylation regulates Rb hyperphosphorylation and inactivation in uveal melanoma.
Meng F, Yuan Y, Ren H, Yue H, Xu B, Qian J
Cancer science 2022 Feb;113(2):622-633
Cancer science 2022 Feb;113(2):622-633
Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders.
Morel C, Christophe A, Maguin-Gaté K, Paoli J, Turner JD, Schroeder H, Grova N
Toxics 2022 Apr 6;10(4)
Toxics 2022 Apr 6;10(4)
H3.3 K36M Mutation as a Clinical Diagnosis Method of Suspected Chondroblastoma Cases.
Mu H, Jiang Y, Xue L, Hua Y, Lin J, Cai Z
Orthopaedic surgery 2021 Apr;13(2):616-622
Orthopaedic surgery 2021 Apr;13(2):616-622
Side-to-side supercharging nerve allograft enhances neurotrophic potential.
Isaacs J, Feger MA, Mallu S, Patel G, Debkowska M, Yager D, Ernst B, Chilukuri S, Moser M, Kurtz C
Muscle & nerve 2020 Feb;61(2):243-252
Muscle & nerve 2020 Feb;61(2):243-252
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.
Bywater MJ, Burkhart DL, Straube J, Sabò A, Pendino V, Hudson JE, Quaife-Ryan GA, Porrello ER, Rae J, Parton RG, Kress TR, Amati B, Littlewood TD, Evan GI, Wilson CH
Nature communications 2020 Apr 14;11(1):1827
Nature communications 2020 Apr 14;11(1):1827
The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain.
Eriksson Y, Boström M, Sandelius Å, Blennow K, Zetterberg H, Kuhn G, Kalm M
Cell death & disease 2018 Jul 10;9(7):775
Cell death & disease 2018 Jul 10;9(7):775
Nerve Tissue Prefabrication Inside the Rat Femoral Bone: Does It Work?
Ozbek Z, Kocman AE, Ozatik O, Soztutar E, Ozkara E, Kose A, Arslantas A, Cetin C
Turkish neurosurgery 2017;27(4):648-655
Turkish neurosurgery 2017;27(4):648-655
Searching for proprioceptors in human facial muscles.
Cobo JL, Abbate F, de Vicente JC, Cobo J, Vega JA
Neuroscience letters 2017 Feb 15;640:1-5
Neuroscience letters 2017 Feb 15;640:1-5
The Ewing's Sarcoma Family of Tumors of Urinary Bladder: A Case Report and Review of the Literature.
Tonyalı Ş, Yazıcı S, Yeşilırmak A, Ergen A
Balkan medical journal 2016 Jul;33(4):462-6
Balkan medical journal 2016 Jul;33(4):462-6
A challenging case of ocular melanoma.
Costache M, Dumitru AV, Pătraşcu OM, Popa-Cherecheanu DA, Bădilă P, Miu JC, Procop A, Popa M, Tampa MŞ, Sajin M, Simionescu O, Cîrstoiu MM
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2015;56(2 Suppl):817-22
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2015;56(2 Suppl):817-22
CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma.
Li L, Xu L, Yan J, Zhen ZJ, Ji Y, Liu CQ, Lau WY, Zheng L, Xu J
Journal of experimental & clinical cancer research : CR 2015 Oct 26;34:129
Journal of experimental & clinical cancer research : CR 2015 Oct 26;34:129
RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development.
Alonso-Curbelo D, Osterloh L, Cañón E, Calvo TG, Martínez-Herranz R, Karras P, Martínez S, Riveiro-Falkenbach E, Romero PO, Rodríguez-Peralto JL, Pastor J, Soengas MS
Oncotarget 2015 May 20;6(14):11848-62
Oncotarget 2015 May 20;6(14):11848-62
ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin.
Cabo R, Alonso P, Viña E, Vázquez G, Gago A, Feito J, Pérez-Moltó FJ, García-Suárez O, Vega JA
Histochemistry and cell biology 2015 Mar;143(3):267-76
Histochemistry and cell biology 2015 Mar;143(3):267-76
Comparison of the cellular composition of two different chondrocyte-seeded biomaterials and the results of their transplantation in humans.
Horák M, Handl M, Podškubka A, Kaňa R, Adler J, Povýšil C
Folia biologica 2014;60(1):1-9
Folia biologica 2014;60(1):1-9
Neurogenic contraction induced by the antiarrhythmic compound, AVE 0118, in rat small mesenteric arteries.
Kun A, Seprényi G, Varró A, Papp JG, Pataricza J
Basic & clinical pharmacology & toxicology 2014 Oct;115(4):315-20
Basic & clinical pharmacology & toxicology 2014 Oct;115(4):315-20
A rare malignancy of the parotid gland in a 13-year-old Taiwanese boy: case report of a mammary analogue secretory carcinoma of the salivary gland with molecular study.
Hwang MJ, Wu PR, Chen CM, Chen CY, Chen CJ
Medical molecular morphology 2014 Mar;47(1):57-61
Medical molecular morphology 2014 Mar;47(1):57-61
Neurophysiological and immunohistochemical studies of IgG anti-GM1 monoclonal antibody on neuromuscular transmission: effects in rat neuromuscular junctions.
Hotta S, Nagaoka T, Taguchi K, Nakatani Y, Utsnomiya I, Masuda Y, Abe K, Yuki N
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 Feb;35(2):205-13
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 Feb;35(2):205-13
Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma.
Shen WR, Wang YP, Chang JY, Yu SY, Chen HM, Chiang CP
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Apr;43(4):258-64
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2014 Apr;43(4):258-64
Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.
Qiu SQ, Wei XL, Huang WH, Wu MY, Qin YS, Li YK, Zhang GJ
Scientific reports 2013;3:2529
Scientific reports 2013;3:2529
The sensory innervation of the human pharynx: searching for mechanoreceptors.
de Carlos F, Cobo J, Macías E, Feito J, Cobo T, Calavia MG, García-Suárez O, Vega JA
Anatomical record (Hoboken, N.J. : 2007) 2013 Nov;296(11):1735-46
Anatomical record (Hoboken, N.J. : 2007) 2013 Nov;296(11):1735-46
Concha bullosa surgery and the distribution of human olfactory neuroepithelium.
Apuhan T, Yildirim YS, Simşek T, Yilmaz F, Yilmaz F
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2013 Mar;270(3):953-7
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2013 Mar;270(3):953-7
Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors.
Kara T, Serinsoz E, Arpaci RB, Gubur O, Orekici G, Ata A, Colak T, Arican A
Pathology, research and practice 2013 Jul;209(7):413-7
Pathology, research and practice 2013 Jul;209(7):413-7
Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Marsh Durban V, Deuker MM, Bosenberg MW, Phillips W, McMahon M
The Journal of clinical investigation 2013 Dec;123(12):5104-18
The Journal of clinical investigation 2013 Dec;123(12):5104-18
Langerhans cells in odontogenic epithelia of odontogenic fibromas.
Wu YC, Wang YP, Chang JY, Chen HM, Sun A, Chiang CP
Journal of the Formosan Medical Association = Taiwan yi zhi 2013 Dec;112(12):756-60
Journal of the Formosan Medical Association = Taiwan yi zhi 2013 Dec;112(12):756-60
Dural angioleiomyoma of the middle cranial fossa: a case report and review of the literature.
Zhou Z, Yu M, Yang S, Zhou J, Sun R, Yang G
Brain tumor pathology 2013 Apr;30(2):117-21
Brain tumor pathology 2013 Apr;30(2):117-21
Histological assessment of mechanoreceptors in Achilles allografts after anterior cruciate ligament reconstruction.
Kim SH, Chun CH, Chun KC, Jo HJ, Kim KM
The American journal of sports medicine 2012 Sep;40(9):2061-5
The American journal of sports medicine 2012 Sep;40(9):2061-5
Evidence of nestin-positive cells in the human cutaneus Meissner and Pacinian corpuscles.
Calavia M, Viña E, Menéndez-González M, López-Muñiz A, Alonso-Guervós M, Cobo J, Otero J, Arias-Carrión O, Vega JA, García-Suárez O
CNS & neurological disorders drug targets 2012 Nov 1;11(7):869-77
CNS & neurological disorders drug targets 2012 Nov 1;11(7):869-77
Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis.
Cabo R, Gálvez MA, San José I, Laurà R, López-Muñiz A, García-Suárez O, Cobo T, Insausti R, Vega JA
Neuroscience letters 2012 May 16;516(2):197-201
Neuroscience letters 2012 May 16;516(2):197-201
Pigmented paraganglioma of the kidney: a case report.
Zhao L, Luo J, Zhang H, Da J
Diagnostic pathology 2012 Jun 28;7:77
Diagnostic pathology 2012 Jun 28;7:77
Cotyledonoid leiomyoma of uterus: a case report.
Ersöz S, Turgutalp H, Mungan S, Güvendı G, Güven S
Turk patoloji dergisi 2011;27(3):257-60
Turk patoloji dergisi 2011;27(3):257-60
Intraglomerular crescentic metastases of malignant melanoma.
Ozluk Y, Kilicaslan I, Kazancioglu R, Demirkesen C, Derin D, Mandel NM
Human pathology 2011 Dec;42(12):2025-8
Human pathology 2011 Dec;42(12):2025-8
Papillary urothelial carcinoma of the bladder with exuberant pseudosarcomatous stromal reaction following radiation therapy.
Ambrosini-Spaltro A, Melissari M
International journal of surgical pathology 2011 Apr;19(2):263-7
International journal of surgical pathology 2011 Apr;19(2):263-7
Copy number alterations and expression profiles of candidate genes in a pulmonary inflammatory myofibroblastic tumor.
Jung SH, Yim SH, Hu HJ, Jung CK, Lee SH, Kim DH, Chung YJ
Lung cancer (Amsterdam, Netherlands) 2010 Nov;70(2):152-7
Lung cancer (Amsterdam, Netherlands) 2010 Nov;70(2):152-7
Extracellular matrix degradation and reduced neural density in children with intrinsic ureteropelvic junction obstruction.
Kaya C, Bogaert G, de Ridder D, Schwentner C, Fritsch H, Oswald J, Radmayr C
Urology 2010 Jul;76(1):185-9
Urology 2010 Jul;76(1):185-9
Differential localization of Acid-sensing ion channels 1 and 2 in human cutaneus pacinian corpuscles.
Calavia MG, Montaño JA, García-Suárez O, Feito J, Guervós MA, Germanà A, Del Valle M, Pérez-Piñera P, Cobo J, Vega JA
Cellular and molecular neurobiology 2010 Aug;30(6):841-8
Cellular and molecular neurobiology 2010 Aug;30(6):841-8
Uterine carcinosarcoma metastatic to the lung as large-cell neuroendocrine carcinoma with synchronous sarcoid granulomatosis.
Froio E, D'Adda T, Fellegara G, Martella E, Caruana P, Pruneri G, Pesci A, Rindi G
Lung cancer (Amsterdam, Netherlands) 2009 Jun;64(3):371-7
Lung cancer (Amsterdam, Netherlands) 2009 Jun;64(3):371-7
Rhabdomyosarcoma arising in a mature cystic teratoma with contralateral serous carcinoma: case report and review of the literature.
Kefeli M, Kandemir B, Akpolat I, Yildirim A, Kokcu A
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2009 Jul;28(4):372-5
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2009 Jul;28(4):372-5
Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats.
Esendagli G, Yilmaz G, Canpinar H, Gunel-Ozcan A, Guc MO, Guc D
Laboratory animals 2009 Jan;43(1):60-4
Laboratory animals 2009 Jan;43(1):60-4
Primary choroid plexus papilloma of the sacral nerve roots.
Boldorini R, Panzarasa G, Girardi P, Monga G
Journal of neurosurgery. Spine 2009 Jan;10(1):51-3
Journal of neurosurgery. Spine 2009 Jan;10(1):51-3
Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?
Behzatoğlu K, Durak H, Canberk S, Aydin O, Huq GE, Oznur M, Ozyalvaçli G, Yildiz P
Diagnostic pathology 2009 Dec 31;4:48
Diagnostic pathology 2009 Dec 31;4:48
Cutaneous metastases of malignant melanoma--how difficult can it be?
Zurac S, Andrei R, Petsakos G, Nichita L, Bastian A, Micu G, Gramadă E, Popp C, Stăniceanu F, Petrescu S, Negroiu G, Giurcăneanu D, Chiţu V
Romanian journal of internal medicine = Revue roumaine de medecine interne 2008;46(4):375-8
Romanian journal of internal medicine = Revue roumaine de medecine interne 2008;46(4):375-8
The coexistence of invasive ductal carcinoma and malignant phyllodes tumor with liposarcomatous and chondrosarcomatous differentiation in the same breast in a post-osteosarcoma case.
Kefeli M, Yildiz L, Akpolat I, Balci P, Ozen N
Pathology, research and practice 2008;204(12):919-23
Pathology, research and practice 2008;204(12):919-23
Metastatic malignant melanoma of the uterine cervix: first diagnosed on liquid-based cytology.
Uzüm N, Köse F, Ataoğlu O
Diagnostic cytopathology 2008 Nov;36(11):769-72
Diagnostic cytopathology 2008 Nov;36(11):769-72
Epithelioid leiomyosarcoma with rhabdoid features.
Yorulmaz G, Erdogan G, Pestereli HE, Savas B, Karaveli FS
Wiener klinische Wochenschrift 2007;119(17-18):557-60
Wiener klinische Wochenschrift 2007;119(17-18):557-60
Myointimoma of the glans penis.
Vardar E, Gunlusoy B, Arslan M, Kececi S
Pathology international 2007 Mar;57(3):158-61
Pathology international 2007 Mar;57(3):158-61
Fine needle aspiration cytology of inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: a case report and review of the literature.
Akbulut M, Gunhan-Bilgen I, Zekioglu O, Duygulu G, Oktay A, Ozdemir N
Cytopathology : official journal of the British Society for Clinical Cytology 2007 Dec;18(6):384-7
Cytopathology : official journal of the British Society for Clinical Cytology 2007 Dec;18(6):384-7
Atherosclerosis research from past to present--on the track of two pathologists with opposing views, Carl von Rokitansky and Rudolf Virchow.
Mayerl C, Lukasser M, Sedivy R, Niederegger H, Seiler R, Wick G
Virchows Archiv : an international journal of pathology 2006 Jul;449(1):96-103
Virchows Archiv : an international journal of pathology 2006 Jul;449(1):96-103
Low grade myofibroblastic sarcoma of tongue: a case report.
Laco J, Simáková E, Slezák R, Tucek L, Mottl R, Spacek J, Ryska A
Ceskoslovenska patologie 2006 Jul;42(3):150-3
Ceskoslovenska patologie 2006 Jul;42(3):150-3
Reduction of GFAP induced by long dark rearing is not restricted to visual cortex.
Corvetti L, Aztiria E, Domenici L
Brain research 2006 Jan 5;1067(1):146-53
Brain research 2006 Jan 5;1067(1):146-53
Recurrent intracranial hemangiopericytoma with multiple metastases.
Cao Y, Zhang MZ, Wang JM, Zhang W, Li G, Zhao JZ
Chinese medical journal 2006 Jan 20;119(2):169-73
Chinese medical journal 2006 Jan 20;119(2):169-73
Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients.
Yesim G, Gupse T, Zafer U, Ahmet A
Journal of hepato-biliary-pancreatic surgery 2005;12(6):502-7
Journal of hepato-biliary-pancreatic surgery 2005;12(6):502-7
Recurrent solitary fibrous tumour in the cerebellopontine angle.
Bikmaz K, Cosar M, Kurtkaya-Yapicier O, Iplikcioglu AC, Gokduman CA
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005 Sep;12(7):829-32
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005 Sep;12(7):829-32
Analysis of prognostic and immunohistochemical factors in gastrointestinal stromal tumors with malignant potential.
Ozgüç H, Yilmazlar T, Yerci O, Soylu R, Tümay V, Filiz G, Zorluoglu A
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2005 Mar;9(3):418-29
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2005 Mar;9(3):418-29
Pulmonary large cell carcinoma with rhabdoid phenotype.
Yilmazbayhan D, Ates LE, Dilege S, Gulluoglu M, Tanju S, Kalayci G
Annals of diagnostic pathology 2005 Aug;9(4):223-6
Annals of diagnostic pathology 2005 Aug;9(4):223-6
Mazabraud's syndrome: intramuscular myxoma associated with fibrous dysplasia.
Kabukcuoglu F, Kabukcuoglu Y, Yilmaz B, Erdem Y, Evren I
Pathology oncology research : POR 2004;10(2):121-3
Pathology oncology research : POR 2004;10(2):121-3
Spindle cell lipoma in an intramuscular lipoma.
Usta U, Türkmen E, Mizrak B, Yildiz D, Güzel Z
Pathology international 2004 Sep;54(9):734-9
Pathology international 2004 Sep;54(9):734-9
Synchronous primary adenocarcinoma and gastrointestinal stromal tumor in the stomach: a report of two cases.
Bircan S, Candir O, Aydin S, Başpinar S, Bülbül M, Kapucuoğlu N, Karahan N, Ciriş M
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2004 Sep;15(3):187-91
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2004 Sep;15(3):187-91
Malignant gastrointestinal stromal tumor of the gallbladder.
Park JK, Choi SH, Lee S, Min KO, Yun SS, Jeon HM
Journal of Korean medical science 2004 Oct;19(5):763-7
Journal of Korean medical science 2004 Oct;19(5):763-7
Collagenous fibroma (desmoplastic fibroblastoma).
Dagli M, Eryilmaz A, Acar A, Kulacoglu S, Akmansu H
Yonsei medical journal 2004 Oct 31;45(5):941-3
Yonsei medical journal 2004 Oct 31;45(5):941-3
Embryonic development of the ganglion plexuses and the concentric layer structure of human gut: a topographical study.
Fu M, Tam PK, Sham MH, Lui VC
Anatomy and embryology 2004 Apr;208(1):33-41
Anatomy and embryology 2004 Apr;208(1):33-41
Concomitant distribution shift of glial GABA transporter and S100 calcium-binding proteins in the rat retina after kainate-induced excitotoxic injury.
Kim D, Kim MJ, Lee JH, Im JO, Won YJ, Yoon SY, Hong HN
Neuroscience letters 2003 Dec 15;353(1):17-20
Neuroscience letters 2003 Dec 15;353(1):17-20
Two intraligamentary lipomatous tumors with immunohistochemical features.
Cinel L, Düşmez D, Nabaei SH, Taner D, Pata O
Acta obstetricia et gynecologica Scandinavica 2002 Aug;81(8):786-7
Acta obstetricia et gynecologica Scandinavica 2002 Aug;81(8):786-7
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of S100 Protein was performed by loading 25 µg of human heart (lane 1), human brain (lane 2) and mouse brain (lane 3) onto an SDS polyacrylamide gel. Proteins were transferred to a PVDF membrane and blocked at 4ºC overnight. The membrane was probed with a S100 Protein monoclonal antibody (Product # MA5-12969) at a dilution of 1:200 overnight at 4°C, washed in TBST, and probed with an HRP-conjugated secondary antibody for 1 hr at room temperature in the dark. Chemiluminescent detection was performed using Pierce ECL Plus Western Blotting Substrate (Product # 32132). Results show a band at ~10 kDa.
- Submitted by
- Invitrogen Antibodies (provider)
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- Western blot was performed using Anti-S100 Monoclonal Antibody (Product # MA5-12969) and a 9kDa band corresponding to S100 was observed across all the cell line and tissues tested. Whole cell extracts (30 µg lysate) of A-375 (Lane 1) and tissue extracts of Mouse Brain (Lane 2), Mouse Heart (Lane 3) and Mouse Lung (Lane 4) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0301BOX). Expression of S100 was observed to be high in Mouse brain as compared to low or negative in Mouse Heart and Mouse Lung. Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The blot was probed with the primary antibody (1:500 dilution) and detected by chemiluminescence with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, HRP (Product # A28177, 1:4000 dilution) using the iBright FL 1000 (Product # A32752). Chemiluminescent detection was performed using Novex® ECL Chemiluminescent Substrate Reagent Kit (Product # WP20005).
Supportive validation
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- Immunofluorescent analysis of S100 Protein (green) showing staining in the cytoplasm of C2C12 cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a S100 Protein monoclonal antibody (Product # MA5-12969) in 3% BSA-PBS at a dilution of 1:50 and incubated overnight at 4ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody in PBS at room temperature in the dark. Actin was stained using Alexa Fluor 554 (red) and nuclei were stained with Hoechst or DAPI (blue). Images were taken at a magnification of 60x.
Supportive validation
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- Formalin-fixed, paraffin-embedded human melanoma stained with S-100 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells.
Supportive validation
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- Fig. 7 The juvenile heart is permissive to Myc-driven proliferation. a Immunofluorescent staining of cardiac troponin, p-H3, Ki67, PCM1, wheat germ agglutinin and aurora B-positive mid-body in the heart of 15-day-old control (no cre) and Myh6-Cre ; R26 LSL-CMER/+ (cre+) mice. Representative images based on analysis of five independent mice. Scale bar represents 10 mum. b Image of the whole heart and a tibia isolated from a 15-day-old control (no cre) and Myh6-Cre ; R26 LSL-CMER/+ (cre+) mice. Scale bar represents 10 mm. Representative images based on analysis on 21 independent mice. c The weight (mg) of hearts (left, R26 LSL-CMER/+ ; no cre, vehicle = 9, no cre tamoxifen = 11; R26 LSL-CMER/+ ; cre+ vehicle n = 7, cre+ tamoxifen n = 10) and quantification of the number of cardiomyocytes (right) isolated from 15-day-old control (no cre, vehicle = 3, no cre tamoxifen = 4) and Myh6-Cre ; R26 LSL-CMER/+ (cre+ vehicle n = 6, cre+ tamoxifen n = 7) mice post administration of tamoxifen or oil (veh), expressed as fold change over the length (mm) of a tibia isolated from the same mouse. Mean and s.e.m. shown. One-way ANOVA with Tukey''s multiple comparisons test; vehicle cre vs tamoxifen cre+, vehicle no cre vs tamoxifen cre+, tamoxifen no cre vs tamoxifen cre+ *** P = 0.001 (weight). Vehicle cre vs tamoxifen cre+ ** P = 0.01, vehicle no cre vs tamoxifen cre+, tamoxifen no cre vs tamoxifen cre+ *** P = 0.001 (cardiomyocyte number). Replicate samples are derived from independent mice. d
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- Fig. 9 Overexpression of Cyclin T1 in the adult heart facilitates Myc-driven proliferation of adult cardiomyocytes. a Immunofluorescent staining of cardiac troponin, p-H3,Ki67, PCM1, wheat germ agglutinin (WGA) and aurora B in control ( R26 LSL-CMER/+ ; no cre) and Myh6-Cre ; R26 LSL-CMER/+ ( R26 LSL-CMER/+ ; cre+) adult mouse heart isolated 4 weeks post systemic infection with an adeno-associated virus encoding Ccnt1 ( AAV9-Ccnt1 ) and 48 h post administration of tamoxifen. Representative images based on analysis of five independent mice. Scale bars represents 10 mum (aurora B) and 50 mum (all others). b Quantification of p-H3-positive nuclei percentage in control ( R26 LSL-CMER/+ ; no cre, n = 9) and Myh6-Cre ; R26 LSL-CMER/+ ( R26 LSL-CMER/+ ; cre+, n = 7) adult mouse heart isolated 4 weeks post systemic infection with an adeno-associated virus encoding Ccnt1 ( AAV9-Ccnt1 ) and 48 h post administration of tamoxifen. Means are taken from five images per mouse; Mean and s.e.m shown. Unpaired t -test; no cre vs cre+ P < 0.0001. c The weight (mg) of hearts isolated from control ( R26 LSL-CMER/+ ; no cre, n = 9 48 h, n = 5 72 h) and Myh6-Cre ; R26 LSL-CMER/+ ( R26 LSL-CMER/+ ; cre+, n = 7 48 h, n = 6 72 h) adult mouse heart 4 weeks post systemic infection with an adeno-associated virus encoding Ccnt1 ( AAV9-Ccnt1 ) and 48 and 72 h post administration of tamoxifen, expressed as fold change over the length (mm) of a tibia isolated from the same mouse. Mean and s.e.m shown. One-wa
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- Fig. 2 Clinical-histological features and H3K36M IHC results of CB cases and suspected case. ( A1-A4 ) The HE features of CB cases. ( B ) The HE features of the suspected case. ( C1-C4 ) The S100 features of the corresponding CB cases. ( D ) The S100 features of the suspected case. ( E1-E4 ) The K36M features of the corresponding CB cases. ( F ) The K36M features of the corresponding the suspected case.